Serum Osmolality Calculator
Estimate the concentration of solutes in the blood to evaluate hydration and electrolyte status.
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Formula
Estimates the number of particles per kilogram of solvent. Sodium, glucose, and urea are the primary contributors.
Worked Example
Frequently Asked Questions
What is a normal serum osmolality?
Usually between 275 and 295 mOsm/kg.
What is the osmolar gap?
It is the difference between the measured osmolality (from a lab) and this calculated value. A gap > 10–12 suggests unmeasured osmoles like ethanol, methanol, or ethylene glycol.
Does ethanol affect the gap?
Yes, ethanol significantly increases measured osmolality, creating a large osmolar gap.
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