METS-IR Calculator (Insulin Action Profiler)

HOMA-IR specifically measures fasting insulin and glucose. METS-IR is a "metabolic proxy" that uses triglycerides, HDL cholesterol, glucose, and BMI to estimate the same insulin resistance state. METS-IR is often preferred for screening because it does not require an expensive insulin lab test.

A METS-IR score of 50.0 or higher is generally considered the threshold for high risk of insulin resistance. Individuals above this score are at increased risk for type 2 diabetes and cardiovascular disease.

Insulin resistance is closely tied to lipid metabolism. High triglycerides and low HDL (the "good" cholesterol) are hallmark signs of "Metabolic Syndrome" and are strong predictors of how the body handles insulin and sugar.

Yes. Since the calculation relies on fasting glucose and triglyceride levels, you should fast (no food or drink except water) for at least 8 to 12 hours before your blood draw.

Research by Bello-Chavolla (2018) and others has shown that METS-IR has high sensitivity (~80%) and specificity (~70%) for detecting insulin resistance, making it an excellent screening alternative to more invasive or expensive clinical tests.

The score can be lowered by improving your lipid profile and insulin sensitivity. This usually involves reducing refined sugar and industrial seed oils, increasing exercise, and maintaining a healthy body weight (BMI).

Yes. Click the "Embed" button at the top of this page to customize the size, colors, and theme, then copy the iframe code. Paste it into any HTML page, WordPress site, or CMS. It is completely free, requires no signup, and works on all devices. You can also visit our embed guide at calculory.com/services/embed-calculators for more details.